Reactome | Abasic sugar-phosphate removal via the single-nucleotide replacement pathway

Schema > Pathway > Entries

Abasic sugar-phosphate removal via the single-nucleotide replacement pathway Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329039
displayName	Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
eventOf	[Pathway:R-CFA-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17135] base-excision repair
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-110360] Recruitment of POLB to the AP site - Canis familiaris [Reaction:R-CFA-110375] Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break - Canis familiaris
inferredFrom	[Pathway:R-HSA-73930] Abasic sugar-phosphate removal via the single-nucleotide replacement pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
precedingEvent	[Pathway:R-CFA-73927] Depurination - Canis familiaris [Pathway:R-CFA-73928] Depyrimidination - Canis familiaris
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-73930
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-110381] Resolution of AP sites via the single-nucleotide replacement pathway
(inferredTo)	[Pathway:R-HSA-73930] Abasic sugar-phosphate removal via the single-nucleotide replacement pathway

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