Reactome | PI3 binds the bacterial surface

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10305232
displayName	PI3 binds the bacterial surface
eventOf	[Pathway:R-CFA-6803157] Antimicrobial peptides - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6810724] PI3 binds the bacterial surface - Homo sapiens
input	[SimpleEntity:R-ALL-6803081] LPS [peptidoglycan-based cell wall] [EntityWithAccessionedSequence:R-CFA-6810812] PI3 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PI3 binds the bacterial surface
output	[Complex:R-CFA-6810759] PI3:LPS [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6810724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-6803157] Antimicrobial peptides
(inferredTo)	[Reaction:R-HSA-6810724] PI3 binds the bacterial surface

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