Reactome | MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5

Schema > Reaction > Entries

MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 Show undefined attributes

catalystActivity	[CatalystActivity:10302781] alpha-mannosidase activity of MAN2C1:Zn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10302783
displayName	MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5
eventOf	[Pathway:R-CFA-8853383] Lysosomal oligosaccharide catabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6799545] MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 - Homo sapiens
input	[SimpleEntity:R-ALL-6799540] alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc [cytosol] 4 × [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5
output	[SimpleEntity:R-ALL-6799543] alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc [cytosol] 4 × [SimpleEntity:R-ALL-429579] Man [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6799545
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8853383] Lysosomal oligosaccharide catabolism
(inferredTo)	[Reaction:R-HSA-6799545] MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5

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