Reactome | HYKK phosphorylates 5HLYS

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HYKK phosphorylates 5HLYS Show undefined attributes

catalystActivity	[CatalystActivity:10299216] hydroxylysine kinase activity of HYKK [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10299218
displayName	HYKK phosphorylates 5HLYS
eventOf	[Pathway:R-CFA-71064] Lysine catabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-5696408] PXLP-K278-PHYKPL tetramer hydrolyses 5PHL - Canis familiaris
inferredFrom	[Reaction:R-HSA-6788611] HYKK phosphorylates 5HLYS - Homo sapiens
input	[SimpleEntity:R-ALL-6788606] 5HLYS [mitochondrial matrix] [SimpleEntity:R-ALL-113573] GTP [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	HYKK phosphorylates 5HLYS (5R)-5-hydroxy-L-lysine + GTP => (5R)-5-phosphooxy-L-lysine + GDP + H(+)
output	[SimpleEntity:R-ALL-5696409] 5PHL [mitochondrial matrix] [SimpleEntity:R-ALL-113525] GDP [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-6788611
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-71064] Lysine catabolism
(precedingEvent)	[Reaction:R-CFA-5696408] PXLP-K278-PHYKPL tetramer hydrolyses 5PHL
(inferredTo)	[Reaction:R-HSA-6788611] HYKK phosphorylates 5HLYS

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