Reactome | IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10298546] transmembrane receptor protein tyrosine kinase activity of IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-CFA-6784324] p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10298540
displayName	IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane]
hasComponent	[Complex:R-CFA-6784348] IL10 dimer:2xIL10RA:p-Y-JAK1 [plasma membrane] 2 × [Complex:R-CFA-6784350] IL10RB:p-Y-TYK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-6784339] IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] - Homo sapiens
maxDepth	4
name	IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2
producedByEvent	[BlackBoxEvent:R-CFA-6784319] JAK1,TYK2 phosphorylate JAK1,TYK2 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-6784339
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-CFA-6784324] p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA
(physicalEntity)	[CatalystActivity:10298546] transmembrane receptor protein tyrosine kinase activity of IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane]
(output)	[BlackBoxEvent:R-CFA-6784319] JAK1,TYK2 phosphorylate JAK1,TYK2
(inferredTo)	[Complex:R-HSA-6784339] IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane]

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