Reactome | ACO1 binds 4Fe-4S

Schema > Reaction > Entries

ACO1 binds 4Fe-4S Show undefined attributes

catalystActivity	[CatalystActivity:10296116] iron-sulfur cluster binding activity of ACO1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10296118
displayName	ACO1 binds 4Fe-4S
eventOf	[Pathway:R-CFA-917937] Iron uptake and transport - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-5690911] ACO1:4Fe-4S isomerises CIT to ISCIT - Canis familiaris
inferredFrom	[Reaction:R-HSA-5690873] ACO1 binds 4Fe-4S - Homo sapiens
input	[OtherEntity:R-ALL-5690881] 4Fe-4S [cytosol] [EntityWithAccessionedSequence:R-CFA-5690899] ACO1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ACO1 binds 4Fe-4S
output	[Complex:R-CFA-5690885] ACO1:4Fe-4S [cytosol]
regulatedBy	[PositiveRegulation:9855362] Positive regulation by 'Fe2+ [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5690873
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-917937] Iron uptake and transport
(precedingEvent)	[Reaction:R-CFA-5690911] ACO1:4Fe-4S isomerises CIT to ISCIT
(inferredTo)	[Reaction:R-HSA-5690873] ACO1 binds 4Fe-4S

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