Reactome | TCF:Beta-catenin binds SOX proteins

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TCF:Beta-catenin binds SOX proteins Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10292194
displayName	TCF:Beta-catenin binds SOX proteins
eventOf	[Pathway:R-CFA-3769402] Deactivation of the beta-catenin transactivating complex - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5665608] TCF:Beta-catenin binds SOX proteins - Homo sapiens
input	[DefinedSet:R-CFA-5665611] SOX4,SOX13,SOX17 [nucleoplasm] [Complex:R-CFA-3299548] TCF/LEF:CTNNB1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TCF:Beta-catenin binds SOX proteins
output	[Complex:R-CFA-5665607] TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm]
precedingEvent	[Reaction:R-CFA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5665608
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-3769402] Deactivation of the beta-catenin transactivating complex
(inferredTo)	[Reaction:R-HSA-5665608] TCF:Beta-catenin binds SOX proteins

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