Reactome | CLEC7A (Dectin-1) induces NFAT activation

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CLEC7A (Dectin-1) induces NFAT activation Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10330993
displayName	CLEC7A (Dectin-1) induces NFAT activation
eventOf	[Pathway:R-CFA-5607764] CLEC7A (Dectin-1) signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-2730872] Activation of Calcineurin - Canis familiaris [BlackBoxEvent:R-CFA-2730849] Calcineurin binds and dephosphorylates NFAT - Canis familiaris [Reaction:R-CFA-2730867] Translocation of CaN:CaM:NFAT to nucleus - Canis familiaris
inferredFrom	[Pathway:R-HSA-5607763] CLEC7A (Dectin-1) induces NFAT activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CLEC7A (Dectin-1) induces NFAT activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-5607763
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5607764] CLEC7A (Dectin-1) signaling
(inferredTo)	[Pathway:R-HSA-5607763] CLEC7A (Dectin-1) induces NFAT activation

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