Reactome | GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG

Schema > Reaction > Entries

GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG Show undefined attributes

catalystActivity	[CatalystActivity:10288622] glutathione gamma-glutamate hydrolase activity of GGT dimers [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10288624
displayName	GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG
eventOf	[Pathway:R-CFA-5423646] Aflatoxin activation and detoxification - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-5433067] DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG - Canis familiaris
inferredFrom	[Reaction:R-HSA-5433072] GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG - Homo sapiens
input	[DefinedSet:R-ALL-5490253] AFXBO-SG,AFNBO-SG [extracellular region] [SimpleEntity:R-ALL-109276] H2O [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG an S-substituted glutathione + H2O => an S-substituted L-cysteinylglycine + L-glutamate
output	[DefinedSet:R-ALL-5490235] AFXBO-CG,AFNBO-CG [extracellular region] [SimpleEntity:R-ALL-210382] L-Glu [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5433072
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5423646] Aflatoxin activation and detoxification
(precedingEvent)	[Reaction:R-CFA-5433067] DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG
(inferredTo)	[Reaction:R-HSA-5433072] GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG

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