Reactome | RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL

Schema > Reaction > Entries

RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL Show undefined attributes

catalystActivity	[CatalystActivity:10288116] all-trans-retinol dehydrogenase (NADP+) activity of RDH11,14,DHRS3,DHRS4 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10288118
displayName	RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL
eventOf	[Pathway:R-CFA-5365859] RA biosynthesis pathway - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5419165] RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL - Homo sapiens
input	[SimpleEntity:R-ALL-975622] atRAL [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL
output	[SimpleEntity:R-ALL-975599] atROL [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-5419165
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5365859] RA biosynthesis pathway
(inferredTo)	[Reaction:R-HSA-5419165] RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL

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