Reactome | WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:171062] early endosome membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10288105
displayName	WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-5368451] CAV1 [early endosome membrane] [EntityWithAccessionedSequence:R-CFA-5368467] FZD5 [early endosome membrane] [GenomeEncodedEntity:R-CFA-5368496] Ghost homologue of p-LRP6 [early endosome membrane] [Complex:R-CFA-1504204] GSK3B:AXIN1 [cytosol] [EntityWithAccessionedSequence:R-CFA-5368483] WNT3A [early endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5368519] WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane] - Homo sapiens
maxDepth	3
name	WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1
producedByEvent	[BlackBoxEvent:R-CFA-5368596] WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-5368519
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-CFA-5368596] WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6
(inferredTo)	[Complex:R-HSA-5368519] WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane]

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