Reactome | AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA

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AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10258675
displayName	AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA
eventOf	[Pathway:R-CFA-450408] AUF1 (hnRNP D0) binds and destabilizes mRNA - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-450551] AUF1 binds translation and heat shock proteins - Canis familiaris
inferredFrom	[Reaction:R-HSA-450434] AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA - Homo sapiens
input	2 × [DefinedSet:R-CFA-450391] AUF1 Dimer (isoform p37 or p40) [cytosol] [OtherEntity:R-ALL-450444] mRNA Transcript Targeted by AUF1(hnRNP D0) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA
output	[Complex:R-CFA-450598] AUF1 Tetramer: Destabilized mRNA Complex [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-450434
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-450408] AUF1 (hnRNP D0) binds and destabilizes mRNA
(precedingEvent)	[Reaction:R-CFA-450551] AUF1 binds translation and heat shock proteins
(inferredTo)	[Reaction:R-HSA-450434] AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA

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