Reactome | RSK activation

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331745
displayName	RSK activation
eventOf	[Pathway:R-CFA-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-CFA-9029434] p-S363,S380,T573 RS6K translocates to the nucleus - Canis familiaris
inferredFrom	[Pathway:R-HSA-444257] RSK activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RSK activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-444257
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
(inferredTo)	[Pathway:R-HSA-444257] RSK activation