Reactome | VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10284962] protein tyrosine kinase activity of VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-4420206] Phosphorylation of SRC-1 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10284951
displayName	VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-191648] SRC [cytosol] [Complex:R-CFA-4420137] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-4420169] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] - Homo sapiens
maxDepth	5
name	VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1
producedByEvent	[Reaction:R-CFA-4420140] SRC1-1 binds SH2D2A and is recruited to VEGFR2 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-4420169
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-4420206] Phosphorylation of SRC-1
(physicalEntity)	[CatalystActivity:10284962] protein tyrosine kinase activity of VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]
(output)	[Reaction:R-CFA-4420140] SRC1-1 binds SH2D2A and is recruited to VEGFR2
(inferredTo)	[Complex:R-HSA-4420169] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]

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