Reactome | Lysosphingolipid and LPA receptors

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Lysosphingolipid and LPA receptors Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10330277
displayName	Lysosphingolipid and LPA receptors
eventOf	[Pathway:R-CFA-373076] Class A/1 (Rhodopsin-like receptors) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-419389] LPA-binding receptors bind LPA - Canis familiaris [Reaction:R-CFA-9690449] S1PR1 bind S1P - Canis familiaris [Reaction:R-CFA-419428] S1PR2-5 bind S1P - Canis familiaris [Reaction:R-CFA-6797630] LRPP4(LRPP1-3,5) hydrolyse LPA - Canis familiaris [Reaction:R-CFA-9678854] S1PR1 binds S1PR1 agonists - Canis familiaris
inferredFrom	[Pathway:R-HSA-419408] Lysosphingolipid and LPA receptors - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Lysosphingolipid and LPA receptors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-419408
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-373076] Class A/1 (Rhodopsin-like receptors)
(inferredTo)	[Pathway:R-HSA-419408] Lysosphingolipid and LPA receptors

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