Reactome | NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]

Schema > Complex > Entries

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:10254524] guanyl-nucleotide exchange factor activity of NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-418850] Activation of Cdc42 - Canis familiaris [Reaction:R-CFA-418856] Activation of Rac1 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10254521
displayName	NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-372654] DOCK1 [cytosol] [Complex:R-CFA-373663] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-418829] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] - Homo sapiens
maxDepth	6
name	NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO
producedByEvent	[Reaction:R-CFA-418858] RhoGTPase GEF's recruited to DCC - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-418829
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-CFA-418850] Activation of Cdc42 [Reaction:R-CFA-418856] Activation of Rac1
(hasComponent)	[Complex:R-CFA-418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] [Complex:R-CFA-418826] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane]
(physicalEntity)	[CatalystActivity:10254524] guanyl-nucleotide exchange factor activity of NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]
(output)	[Reaction:R-CFA-418858] RhoGTPase GEF's recruited to DCC
(inferredTo)	[Complex:R-HSA-418829] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]

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