Reactome | Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline

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Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline Show undefined attributes

catalystActivity	[CatalystActivity:10253976] alpha2-adrenergic receptor activity of ADRA2A,C [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10253978
displayName	Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline
eventOf	[Pathway:R-CFA-400042] Adrenaline,noradrenaline inhibits insulin secretion - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-400071] Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline - Homo sapiens
input	[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region] [DefinedSet:R-CFA-400086] ADRA2A,C [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline
output	[Complex:R-CFA-400090] ADRA2A,C:ADR,NAd [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-400071
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-400042] Adrenaline,noradrenaline inhibits insulin secretion
(inferredTo)	[Reaction:R-HSA-400071] Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline

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