Reactome | EPHBs bind EFNBs

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10284197
displayName	EPHBs bind EFNBs
eventOf	[Pathway:R-CFA-2682334] EPH-Ephrin signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-3928597] EPH:EFN dimers tetramerise - Canis familiaris
inferredFrom	[Reaction:R-HSA-3928624] EPHBs bind EFNBs - Homo sapiens
input	[DefinedSet:R-CFA-3928378] EFNBs [plasma membrane] [DefinedSet:R-CFA-3928335] EPHBs [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	EPHBs bind EFNBs Ephrin-B ligands interacts with EPHB receptors
output	[Complex:R-CFA-3928331] EPHBs:EFNBs [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-3928624
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-2682334] EPH-Ephrin signaling
(precedingEvent)	[Reaction:R-CFA-3928597] EPH:EFN dimers tetramerise
(inferredTo)	[Reaction:R-HSA-3928624] EPHBs bind EFNBs

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