Reactome | BTLA interacts with HVEM

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10252907
displayName	BTLA interacts with HVEM
eventOf	[Pathway:R-CFA-9927353] Co-inhibition by BTLA - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-389523] BTLA interacts with HVEM - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-197774] BTLA [plasma membrane] [EntityWithAccessionedSequence:R-CFA-198101] TNFRSF14 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	BTLA interacts with HVEM
output	[Complex:R-CFA-389525] BTLA-HVEM complex [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-389523
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-9927353] Co-inhibition by BTLA
(inferredTo)	[Reaction:R-HSA-389523] BTLA interacts with HVEM

Cite Us!