Reactome | DCC interacting NCK-1

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DCC interacting NCK-1 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10249252
displayName	DCC interacting NCK-1
eventOf	[Pathway:R-CFA-418885] DCC mediated attractive signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-418858] RhoGTPase GEF's recruited to DCC - Canis familiaris
inferredFrom	[Reaction:R-HSA-373716] DCC interacting NCK-1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-197954] NCK1 [cytosol] [Complex:R-CFA-374551] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DCC interacting NCK-1
output	[Complex:R-CFA-373663] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane]
precedingEvent	[Reaction:R-CFA-374701] Phosphorylation of DCC by Fyn - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-373716
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-418885] DCC mediated attractive signaling
(precedingEvent)	[Reaction:R-CFA-418858] RhoGTPase GEF's recruited to DCC
(inferredTo)	[Reaction:R-HSA-373716] DCC interacting NCK-1