Reactome | Caspase-mediated cleavage of claspin

Schema > Reaction > Entries

Caspase-mediated cleavage of claspin Show undefined attributes

catalystActivity	[CatalystActivity:10248755] cysteine-type endopeptidase activity of active caspase-7 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10248757
displayName	Caspase-mediated cleavage of claspin
eventOf	[Pathway:R-CFA-111465] Apoptotic cleavage of cellular proteins - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-351936] Caspase-mediated cleavage of claspin - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-176282] CLSPN [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase-mediated cleavage of claspin
output	[EntityWithAccessionedSequence:R-CFA-351929] CLSPN [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-351935] CLSPN [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-CFA-9029680] Caspase-7 translocates to the nucleus - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-351936
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-111465] Apoptotic cleavage of cellular proteins
(inferredTo)	[Reaction:R-HSA-351936] Caspase-mediated cleavage of claspin

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