Reactome | TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10302743] protein serine/threonine kinase activity of TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-CFA-6799409] HIPK2 phosphorylates TP53 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10281678
displayName	TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm]
hasComponent	[Complex:R-CFA-6799392] p-HIPK2:PIN1 [nucleoplasm] [Complex:R-CFA-3222171] p-S15,S20-TP53 Tetramer [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-3215226] TP53INP1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-3215242] TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm] - Homo sapiens
maxDepth	3
name	TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53
producedByEvent	[Reaction:R-CFA-3215251] TP53INP1 and HIPK2 bind TP53 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-3215242
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-6799409] HIPK2 phosphorylates TP53
(physicalEntity)	[CatalystActivity:10302743] protein serine/threonine kinase activity of TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm]
(output)	[Reaction:R-CFA-3215251] TP53INP1 and HIPK2 bind TP53
(inferredTo)	[Complex:R-HSA-3215242] TP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53 [nucleoplasm]

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