Reactome | RMTs methylate histone arginines

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RMTs methylate histone arginines Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331029
displayName	RMTs methylate histone arginines
eventOf	[Pathway:R-CFA-3247509] Chromatin modifying enzymes - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-3215406] PRMT5 binds WDR77 - Canis familiaris [Reaction:R-CFA-3215385] CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 - Canis familiaris [Reaction:R-CFA-5205799] CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) - Canis familiaris [Reaction:R-CFA-5661117] CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 - Canis familiaris [Reaction:R-CFA-3215426] COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 - Canis familiaris [Reaction:R-CFA-5205861] COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) - Canis familiaris [BlackBoxEvent:R-CFA-5216234] PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) - Canis familiaris [Reaction:R-CFA-5218952] PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) - Canis familiaris [Reaction:R-CFA-5225602] WDR5 binds Me2sR3-replicative histone H3 - Canis familiaris [Reaction:R-CFA-5212679] DNMT3A binds Me2sR4-HIST1H4 - Canis familiaris [Reaction:R-CFA-3215448] SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity - Canis familiaris [Reaction:R-CFA-5205798] PRMT1,PRMT6 methylate arginine-4 of histone H4 - Canis familiaris [Reaction:R-CFA-5661126] PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 - Canis familiaris [Reaction:R-CFA-5205822] CARM1 methylates arginine-18 (H3R17) of histone H3 - Canis familiaris [Reaction:R-CFA-5229010] CARM1 methylates arginine-27 of histone H3 (H3R26) - Canis familiaris [Reaction:R-CFA-5205824] CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) - Canis familiaris [Reaction:R-CFA-5205820] PRMT6 methylates arginine-4 of histone H2A (H2AR3) - Canis familiaris [Reaction:R-CFA-5205867] PRMT1 methylates arginine-12 of histone H2A (H2AR11) - Canis familiaris [Reaction:R-CFA-5229203] PRMT6 methylates histone H2A arginine-30 (H2AR29) - Canis familiaris [Reaction:R-CFA-8879123] PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 - Canis familiaris
inferredFrom	[Pathway:R-HSA-3214858] RMTs methylate histone arginines - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RMTs methylate histone arginines
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-3214858
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-3247509] Chromatin modifying enzymes
(inferredTo)	[Pathway:R-HSA-3214858] RMTs methylate histone arginines

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