Reactome | MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin

Schema > Reaction > Entries

MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin Show undefined attributes

catalystActivity	[CatalystActivity:10281576] methionine synthase activity of MTRR:MTR:cob(I)alamin [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10281578
displayName	MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin
eventOf	[Pathway:R-CFA-9759218] Cobalamin (Cbl) metabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3149539] MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin - Homo sapiens
input	[SimpleEntity:R-ALL-200665] 5-methyl-THF [cytosol] [Complex:R-CFA-3149516] MTRR:MTR:cob(I)alamin [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin
output	[Complex:R-CFA-3149551] MTRR:MTR:MeCbl [cytosol] [SimpleEntity:R-ALL-111355] THF [cytosol]
precedingEvent	[Reaction:R-CFA-174374] MTR transfers CH3 from MeCbl to HCYS - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-3149539
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9759218] Cobalamin (Cbl) metabolism
(inferredTo)	[Reaction:R-HSA-3149539] MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin

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