Reactome | AGRN binds Beta amyloid fibril via GAG chains

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10279628
displayName	AGRN binds Beta amyloid fibril via GAG chains
eventOf	[Pathway:R-CFA-3000178] ECM proteoglycans - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2467665] AGRN binds Beta amyloid fibril via GAG chains - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-375056] AGRN [extracellular region] [Polymer:R-CFA-976748] Beta amyloid fibril [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	AGRN binds Beta amyloid fibril via GAG chains
output	[Complex:R-CFA-2467662] AGRN:Beta amyloid fibril [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-2467665
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-3000178] ECM proteoglycans
(inferredTo)	[Reaction:R-HSA-2467665] AGRN binds Beta amyloid fibril via GAG chains

Cite Us!