Reactome | RDH5 oxidises 11cROL to 11cRAL

Schema > Reaction > Entries

RDH5 oxidises 11cROL to 11cRAL Show undefined attributes

catalystActivity	[CatalystActivity:10279445] all-trans-retinol dehydrogenase (NAD+) activity of RDH5(1-318)-like Proteins [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10279447
displayName	RDH5 oxidises 11cROL to 11cRAL
eventOf	[Pathway:R-CFA-2453902] The canonical retinoid cycle in rods (twilight vision) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-8960973] RLBP1:11cRAL dissociates - Canis familiaris
inferredFrom	[Reaction:R-HSA-2454081] RDH5 oxidises 11cROL to 11cRAL - Homo sapiens
input	[SimpleEntity:R-ALL-29360] NAD+ [cytosol] [Complex:R-CFA-2454078] RLBP1:11cROL [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RDH5 oxidises 11cROL to 11cRAL RDH5 oxidises 11-cis-retinol to 11-cis-retinal
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol] [Complex:R-CFA-2454060] RLBP1:11cRAL [cytosol]
precedingEvent	[Reaction:R-CFA-2454264] 11cROL binds to RLBP1 to form RLBP1:11cROL - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-2454081
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2453902] The canonical retinoid cycle in rods (twilight vision)
(precedingEvent)	[Reaction:R-CFA-8960973] RLBP1:11cRAL dissociates
(inferredTo)	[Reaction:R-HSA-2454081] RDH5 oxidises 11cROL to 11cRAL

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