Reactome | MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane]

compartment	[Compartment:5263265] lumenal side of endoplasmic reticulum membrane
componentOf	[Complex:R-CFA-8980062] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] - Canis familiaris [Complex:R-CFA-8980062] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] - Canis familiaris [Complex:R-CFA-8980063] alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-2213241] Formation of nonameric complex - Canis familiaris [Reaction:R-CFA-2213241] Formation of nonameric complex - Canis familiaris [Reaction:R-CFA-2130478] Interaction of invariant chain trimer and MHC II alpha beta dimer - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10276741
displayName	MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane]
hasComponent	[DefinedSet:R-CFA-2130718] HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] [DefinedSet:R-CFA-2130672] HLA II beta chain [lumenal side of endoplasmic reticulum membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2213186] MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] - Homo sapiens
maxDepth	3
name	MHC II alpha beta heterodimer
producedByEvent	[Reaction:R-CFA-2213239] Formation of MHC II alpha beta heterodimer - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-2213186
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-2213241] Formation of nonameric complex [Reaction:R-CFA-2130478] Interaction of invariant chain trimer and MHC II alpha beta dimer
(output)	[Reaction:R-CFA-2213239] Formation of MHC II alpha beta heterodimer
(hasComponent)	[Complex:R-CFA-8980062] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] [Complex:R-CFA-8980063] alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] [Complex:R-CFA-8951502] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] [Complex:R-CFA-2213212] alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] [Complex:R-CFA-2130477] Nonameric complex [lumenal side of endoplasmic reticulum membrane]
(inferredTo)	[Complex:R-HSA-2213186] MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane]

MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] Show undefined attributes

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