Reactome | RNF111 binds SMAD7

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10277925
displayName	RNF111 binds SMAD7
eventOf	[Pathway:R-CFA-2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2186771] RNF111 binds SMAD7 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-2186765] RNF111 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-178197] SMAD7 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RNF111 binds SMAD7
output	[Complex:R-CFA-2186769] SMAD7:RNF111 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-2186771
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
(inferredTo)	[Reaction:R-HSA-2186771] RNF111 binds SMAD7