Reactome | Fibrillin-1 [extracellular region]

Schema > Polymer > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-CFA-2396200] Fibrilin-1:Fibrilin-binding integrins [plasma membrane] - Canis familiaris [Complex:R-CFA-2396177] LTBPs:Fibrillin-1 [extracellular region] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-2328037] Fibrillin-1 binds integrins - Canis familiaris [Reaction:R-CFA-2514772] Fibrillin-1 degradation by MMP3, CTSK, CTSL2 - Canis familiaris [Reaction:R-CFA-2514831] Fibrillin-1 degradation by MMP14 - Canis familiaris [Reaction:R-CFA-2328033] Fibrillin-1 binds latent TGF-beta - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10269646
displayName	Fibrillin-1 [extracellular region]
inDisease	false
inferredFrom	[Polymer:R-HSA-2159874] Fibrillin-1 [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-CFA-2159839] Fibrillin 1,2,(3) [extracellular region] - Canis familiaris
name	Fibrillin-1
repeatedUnit	[EntityWithAccessionedSequence:R-CFA-2159853] FBN1 [extracellular region]
schemaClass	Polymer
species	[Species:49646] Canis familiaris
stId	R-CFA-2159874
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-2328037] Fibrillin-1 binds integrins [Reaction:R-CFA-2514772] Fibrillin-1 degradation by MMP3, CTSK, CTSL2 [Reaction:R-CFA-2514831] Fibrillin-1 degradation by MMP14 [Reaction:R-CFA-2328033] Fibrillin-1 binds latent TGF-beta
(hasComponent)	[Complex:R-CFA-2396200] Fibrilin-1:Fibrilin-binding integrins [plasma membrane] [Complex:R-CFA-2396177] LTBPs:Fibrillin-1 [extracellular region]
(hasMember)	[CandidateSet:R-CFA-2159839] Fibrillin 1,2,(3) [extracellular region]
(inferredTo)	[Polymer:R-HSA-2159874] Fibrillin-1 [extracellular region]