Reactome | CYP26C1 4-hydroxylates 9cRA

Schema > Reaction > Entries

CYP26C1 4-hydroxylates 9cRA Show undefined attributes

catalystActivity	[CatalystActivity:10247538] retinoic acid 4-hydroxylase activity of CYP26C1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10247540
displayName	CYP26C1 4-hydroxylates 9cRA
eventOf	[Pathway:R-CFA-211916] Vitamins - Canis familiaris [Pathway:R-CFA-5365859] RA biosynthesis pathway - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-211923] CYP26C1 4-hydroxylates 9cRA - Homo sapiens
input	[SimpleEntity:R-ALL-5362520] 9cRA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP26C1 4-hydroxylates 9cRA
output	[SimpleEntity:R-ALL-5362524] 4OH-9cRA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-CFA-5696101] ALDH8A1 oxidises 9cRAL to 9cRA - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-211923
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-5365859] RA biosynthesis pathway [Pathway:R-CFA-211916] Vitamins
(inferredTo)	[Reaction:R-HSA-211923] CYP26C1 4-hydroxylates 9cRA