Reactome | Trans-homophilic interaction of PECAM-1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10247085
displayName	Trans-homophilic interaction of PECAM-1
eventOf	[Pathway:R-CFA-210990] PECAM1 interactions - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-210285] Trans-homophilic interaction of PECAM-1 - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-CFA-114686] PECAM1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Trans-homophilic interaction of PECAM-1
output	[Complex:R-CFA-210238] PECAM1 dimer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-210285
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-210990] PECAM1 interactions
(inferredTo)	[Reaction:R-HSA-210285] Trans-homophilic interaction of PECAM-1

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