Reactome | CD19 Signalosome [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10276019] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of CD19 Signalosome [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10276018
displayName	CD19 Signalosome [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-202993] GRB2 [plasma membrane] [EntityWithAccessionedSequence:R-CFA-2076270] phospho-CD19 [plasma membrane] [Complex:R-CFA-1045152] PIK3CD:PIK3R1 [plasma membrane] [EntityWithAccessionedSequence:R-CFA-1045153] VAV1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2076233] CD19 Signalosome [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-CFA-2316432] Activator:PI3K [plasma membrane] - Canis familiaris
name	CD19 Signalosome
producedByEvent	[Reaction:R-CFA-9606887] p-CD19:VAV binds PI3K and GRB2 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-2076233
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10276019] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of CD19 Signalosome [plasma membrane]
(output)	[Reaction:R-CFA-9606887] p-CD19:VAV binds PI3K and GRB2
(hasMember)	[DefinedSet:R-CFA-2316432] Activator:PI3K [plasma membrane]
(inferredTo)	[Complex:R-HSA-2076233] CD19 Signalosome [plasma membrane]