Reactome | clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]

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clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:10275424] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] - Canis familiaris [Complex:R-CFA-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR - Canis familiaris [Reaction:R-CFA-2029273] PI3K binds to p-6Y-SYK - Canis familiaris [Reaction:R-CFA-2029270] Recruitment of PLCgamma to membrane - Canis familiaris [Reaction:R-CFA-2029458] Recruitment of VAV1 to p-6Y-SYK - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10275394
displayName	clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
hasComponent	[Complex:R-CFA-2029128] clustered IgG-Ag:p-FCGRs [plasma membrane] [EntityWithAccessionedSequence:R-CFA-1861712] phospho-SYK [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - Homo sapiens
maxDepth	8
name	clustered IgG-Ag:p-FCGRs:p-6Y-SYK
producedByEvent	[Reaction:R-CFA-2029272] Release of PLCG from FCGR - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-2029158
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-CFA-2029458] Recruitment of VAV1 to p-6Y-SYK [Reaction:R-CFA-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR [Reaction:R-CFA-2029273] PI3K binds to p-6Y-SYK [Reaction:R-CFA-2029270] Recruitment of PLCgamma to membrane
(physicalEntity)	[CatalystActivity:10275424] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
(hasComponent)	[Complex:R-CFA-2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] [Complex:R-CFA-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] [Complex:R-CFA-2029131] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] [Complex:R-CFA-2029149] PI3K:p-6Y-SYK [plasma membrane] [Complex:R-CFA-2029137] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] [Complex:R-CFA-2029156] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane]
(output)	[Reaction:R-CFA-2029272] Release of PLCG from FCGR
(inferredTo)	[Complex:R-HSA-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]

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