Reactome | CRK:DOCK180:ELMO1,ELMO2 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] - Canis familiaris [Complex:R-CFA-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR - Canis familiaris [Reaction:R-CFA-8848611] Phosphorylated PXN recruits the CRK complex - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10275587
displayName	CRK:DOCK180:ELMO1,ELMO2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-CFA-2980677] CRK [cytosol] [EntityWithAccessionedSequence:R-CFA-372654] DOCK1 [cytosol] [DefinedSet:R-CFA-372640] ELMO1,ELMO2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2029141] CRK:DOCK180:ELMO1,ELMO2 [cytosol] - Homo sapiens
maxDepth	3
name	CRK:DOCK180:ELMO1,ELMO2
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-2029141
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(activeUnit)	[CatalystActivity:10275590] guanyl-nucleotide exchange factor activity of CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] [CatalystActivity:10286594] guanyl-nucleotide exchange factor activity of CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane]
(input)	[Reaction:R-CFA-2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR [Reaction:R-CFA-8848611] Phosphorylated PXN recruits the CRK complex
(hasComponent)	[Complex:R-CFA-2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] [Complex:R-CFA-5218776] CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] [Complex:R-CFA-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol]
(inferredTo)	[Complex:R-HSA-2029141] CRK:DOCK180:ELMO1,ELMO2 [cytosol]

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