Reactome | CREB phosphorylation

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329829
displayName	CREB phosphorylation
eventOf	[Pathway:R-CFA-198725] Nuclear Events (kinase and transcription factor activation) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-199935] MSK1 activates CREB - Canis familiaris [Reaction:R-CFA-199910] MSK1 activates ATF1 - Canis familiaris [Reaction:R-CFA-199895] RSK1/2/3 phosphorylates CREB at Serine 119 - Canis familiaris
inferredFrom	[Pathway:R-HSA-199920] CREB phosphorylation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CREB phosphorylation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-199920
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-198725] Nuclear Events (kinase and transcription factor activation) [Pathway:R-CFA-450282] MAPK targets/ Nuclear events mediated by MAP kinases
(inferredTo)	[Pathway:R-HSA-199920] CREB phosphorylation