Reactome | EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10240830] protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-182935] EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-182969] Phosphorylation of CBL (EGFR:CBL) - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10240824
displayName	EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-CFA-112199] CBL [cytosol] [Complex:R-CFA-9624425] EGF-like ligands:p-6Y EGFR dimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-182960] EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] - Homo sapiens
maxDepth	4
name	EGF-like ligands:p-6Y-EGFR:CBL
producedByEvent	[Reaction:R-CFA-183055] Binding of CBL to EGFR - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-182960
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-CFA-182935] EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] [Complex:R-CFA-182939] EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane]
(input)	[Reaction:R-CFA-182969] Phosphorylation of CBL (EGFR:CBL)
(physicalEntity)	[CatalystActivity:10240830] protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]
(output)	[Reaction:R-CFA-183055] Binding of CBL to EGFR
(inferredTo)	[Complex:R-HSA-182960] EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]

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