Reactome | TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-2134534] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] - Canis familiaris [Complex:R-CFA-173509] TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-173512] I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) - Canis familiaris [Reaction:R-CFA-170835] An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 - Canis familiaris [Reaction:R-CFA-173483] BAMBI interferes with the interaction of type I receptor with type II receptor - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10238909
displayName	TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]
hasComponent	[Complex:R-CFA-170852] Dimeric TGFB1 [extracellular region] [Complex:R-CFA-170863] p-TGFBR1 [plasma membrane] [Complex:R-CFA-170866] TGFBR2 homodimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] - Homo sapiens
maxDepth	3
name	TGFB1:TGFBR2:p-TGFBR1
producedByEvent	[Reaction:R-CFA-170843] TGFBR2 phosphorylates TGFBR1 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-170841
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-CFA-2134534] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] [Complex:R-CFA-173509] TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] [Complex:R-CFA-2127564] TGFB1:p-TGFBR:STRAP [plasma membrane] [Complex:R-CFA-173476] TGFB1: p-TGFBR: I-SMAD7 [plasma membrane]
(input)	[Reaction:R-CFA-173483] BAMBI interferes with the interaction of type I receptor with type II receptor [Reaction:R-CFA-173512] I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) [Reaction:R-CFA-170835] An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
(output)	[Reaction:R-CFA-170843] TGFBR2 phosphorylates TGFBR1
(inferredTo)	[Complex:R-HSA-170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane]