Reactome | NPC transports GCK1:GCKR from cytosol to nucleoplasm

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NPC transports GCK1:GCKR from cytosol to nucleoplasm Show undefined attributes

catalystActivity	[CatalystActivity:10238871] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope]
category	omitted
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10238873
displayName	NPC transports GCK1:GCKR from cytosol to nucleoplasm
eventOf	[Pathway:R-CFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-170810] nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) - Canis familiaris
goBiologicalProcess	[GO_BiologicalProcess:11054] protein import into nucleus
inferredFrom	[BlackBoxEvent:R-HSA-170796] NPC transports GCK1:GCKR from cytosol to nucleoplasm - Homo sapiens
input	[Complex:R-CFA-170827] GCK1:GCKR complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NPC transports GCK1:GCKR from cytosol to nucleoplasm Transport of glucokinase (GCK1):GCKR complex to the nucleus
output	[Complex:R-CFA-170804] GCK1:GCKR complex [nucleoplasm]
precedingEvent	[Reaction:R-CFA-170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex - Canis familiaris
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49646] Canis familiaris
stId	R-CFA-170796
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein
(precedingEvent)	[Reaction:R-CFA-170810] nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR)
(inferredTo)	[BlackBoxEvent:R-HSA-170796] NPC transports GCK1:GCKR from cytosol to nucleoplasm

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