Reactome | Prolonged ERK activation events

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329439
displayName	Prolonged ERK activation events
eventOf	[Pathway:R-CFA-187687] Signalling to ERKs - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21714] MAPK cascade
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-CFA-170968] Frs2-mediated activation - Canis familiaris [Pathway:R-CFA-170984] ARMS-mediated activation - Canis familiaris
inferredFrom	[Pathway:R-HSA-169893] Prolonged ERK activation events - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Prolonged ERK activation events
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-169893
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-187687] Signalling to ERKs
(inferredTo)	[Pathway:R-HSA-169893] Prolonged ERK activation events

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