Reactome | PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane

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PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane Show undefined attributes

catalystActivity	[CatalystActivity:10270885] 1-phosphatidylinositol-3-kinase activity of PIK3C2A/3 [cytosol]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10270902
displayName	PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane
eventOf	[Pathway:R-CFA-1660514] Synthesis of PIPs at the Golgi membrane - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-1676114] PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane - Canis familiaris
inferredFrom	[Reaction:R-HSA-1675961] PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-1524146] PI [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1806159] PI3P [Golgi membrane]
precedingEvent	[Reaction:R-CFA-1676114] PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane - Canis familiaris [Reaction:R-CFA-1483087] PI is exchanged with PC by PITPNB - Canis familiaris [Reaction:R-CFA-1676133] PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1675961
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1660514] Synthesis of PIPs at the Golgi membrane
(precedingEvent)	[Reaction:R-CFA-1676114] PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane
(inferredTo)	[Reaction:R-HSA-1675961] PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane

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