Reactome | ARSB hydrolyses DS

Schema > Reaction > Entries

ARSB hydrolyses DS Show undefined attributes

catalystActivity	[CatalystActivity:10270148] N-acetylgalactosamine-4-sulfatase activity of ARSB:Ca2+ [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10270150
displayName	ARSB hydrolyses DS
eventOf	[Pathway:R-CFA-2024101] CS/DS degradation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-1793182] IDS hydrolyses dermatan sulfate (Chebi:63517 chain) - Canis familiaris [Reaction:R-CFA-1793209] HYAL1-4 hydrolyze chondroitin chains - Canis familiaris
goBiologicalProcess	[GO_BiologicalProcess:21608] dermatan sulfate proteoglycan catabolic process
inferredFrom	[Reaction:R-HSA-1606789] ARSB hydrolyses DS - Homo sapiens
input	[SimpleEntity:R-ALL-2065231] ChEBI:63519 chain [lysosomal lumen] [SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ARSB hydrolyses DS
output	[SimpleEntity:R-ALL-2065213] ChEBI:63517 chain [lysosomal lumen] [SimpleEntity:R-ALL-1606845] SO4(2-) [lysosomal lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1606789
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2024101] CS/DS degradation
(precedingEvent)	[Reaction:R-CFA-1793209] HYAL1-4 hydrolyze chondroitin chains [Reaction:R-CFA-1793182] IDS hydrolyses dermatan sulfate (Chebi:63517 chain)
(inferredTo)	[Reaction:R-HSA-1606789] ARSB hydrolyses DS