Reactome | G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)

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G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) Show undefined attributes

catalystActivity	[CatalystActivity:10268782] glycerol-3-phosphate O-acyltransferase activity of GPAM/GPAT2 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10268784
displayName	G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)
eventOf	[Pathway:R-CFA-1483166] Synthesis of PA - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Canis familiaris
inferredFrom	[Reaction:R-HSA-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) - Homo sapiens
input	[SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol] [SimpleEntity:R-ALL-76114] G3P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)
output	[SimpleEntity:R-ALL-1500580] 1-acyl LPA [mitochondrial outer membrane] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
precedingEvent	[Reaction:R-CFA-75889] DHAP is converted to G3P by GPD1/GPD1L - Canis familiaris [Reaction:R-CFA-75887] Conversion of Glycerol to Glycerol-3-phosphate - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1482695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1483166] Synthesis of PA
(precedingEvent)	[Reaction:R-CFA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM)
(inferredTo)	[Reaction:R-HSA-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM)

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