Reactome | ABCA4 mediates atRAL transport

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ABCA4 mediates atRAL transport Show undefined attributes

catalystActivity	[CatalystActivity:10268324] retinol transmembrane transporter activity of ABCA4 [photoreceptor disc membrane]
category	transition
compartment	[Compartment:74000] photoreceptor outer segment membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10268326
displayName	ABCA4 mediates atRAL transport
eventOf	[Pathway:R-CFA-382556] ABC-family protein mediated transport - Canis familiaris [Pathway:R-CFA-2453902] The canonical retinoid cycle in rods (twilight vision) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-2464822] RDH12 reduces atRAL to atROL - Canis familiaris
inferredFrom	[Reaction:R-HSA-1467466] ABCA4 mediates atRAL transport - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-2466098] atRAL [photoreceptor disc membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCA4 mediates atRAL transport atRAL(membrane) is transported to atRAL(cytosol) by ABCA4
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-975622] atRAL [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1467466
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2453902] The canonical retinoid cycle in rods (twilight vision) [Pathway:R-CFA-382556] ABC-family protein mediated transport
(precedingEvent)	[Reaction:R-CFA-2464822] RDH12 reduces atRAL to atROL
(inferredTo)	[Reaction:R-HSA-1467466] ABCA4 mediates atRAL transport

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