Reactome | Transmission across Chemical Synapses

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Transmission across Chemical Synapses Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10328663
displayName	Transmission across Chemical Synapses
eventOf	[TopLevelPathway:R-CFA-112316] Neuronal System - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-CFA-112308] Presynaptic depolarization and calcium channel opening - Canis familiaris [Pathway:R-CFA-112310] Neurotransmitter release cycle - Canis familiaris [Pathway:R-CFA-112311] Neurotransmitter clearance - Canis familiaris [Pathway:R-CFA-112313] Neurotransmitter uptake and metabolism In glial cells - Canis familiaris [Pathway:R-CFA-112314] Neurotransmitter receptors and postsynaptic signal transmission - Canis familiaris
inferredFrom	[Pathway:R-HSA-112315] Transmission across Chemical Synapses - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	7
name	Transmission across Chemical Synapses
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-112315
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-CFA-112316] Neuronal System
(inferredTo)	[Pathway:R-HSA-112315] Transmission across Chemical Synapses

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