Reactome | Inactivation of PLC beta

Schema > Reaction > Entries

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10234206
displayName	Inactivation of PLC beta
eventOf	[Pathway:R-CFA-112043] PLC beta mediated events - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-112037] Inactivation of PLC beta - Homo sapiens
input	[Complex:R-CFA-111856] Activated PLC beta 1/4 [plasma membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Inactivation of PLC beta
output	[Complex:R-CFA-111864] G-protein alpha:GDP [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol] [DefinedSet:R-CFA-111854] PLC-beta [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-112037
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-112043] PLC beta mediated events
(inferredTo)	[Reaction:R-HSA-112037] Inactivation of PLC beta

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