Reactome | RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] - Canis familiaris [Complex:R-CFA-113722] Aborted elongation complex after arrest [nucleoplasm] - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10229133
displayName	RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-CFA-83714] Ghost homologue of POLR2F [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-113420] phospho-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63504] POLR2B [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63506] POLR2C [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63508] POLR2D [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-83713] POLR2E [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63517] POLR2G [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63523] POLR2H [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63525] POLR2I [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63531] POLR2J [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-63537] POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-83715] POLR2L [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] - Homo sapiens
maxDepth	2
name	RNA Polymerase II holoenzyme complex (hyperphosphorylated)
producedByEvent	[Reaction:R-CFA-113429] Elongating transcript encounters a lesion in the template - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-109909
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-CFA-113429] Elongating transcript encounters a lesion in the template
(hasComponent)	[Complex:R-CFA-113722] Aborted elongation complex after arrest [nucleoplasm] [Complex:R-CFA-6781822] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-CFA-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] [Complex:R-CFA-113425] RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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