Reactome | Formation of the PA28-alpha-beta regulatory particle

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Formation of the PA28-alpha-beta regulatory particle Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10991770
displayName	Formation of the PA28-alpha-beta regulatory particle
eventOf	[Pathway:R-CEL-9907900] Proteasome assembly - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-9908709] Formation of the PA28-alpha-beta-20S proteasome - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-9908686] Formation of the PA28-alpha-beta regulatory particle - Homo sapiens
input	4 × [EntityWithAccessionedSequence:R-CEL-68812] psme-3 [cytosol] 3 × [EntityWithAccessionedSequence:R-CEL-68814] psme-3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of the PA28-alpha-beta regulatory particle
output	[Complex:R-CEL-9908690] PA28-alpha-beta heteroheptamer [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9908686
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-9907900] Proteasome assembly
(precedingEvent)	[Reaction:R-CEL-9908709] Formation of the PA28-alpha-beta-20S proteasome
(inferredTo)	[Reaction:R-HSA-9908686] Formation of the PA28-alpha-beta regulatory particle

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