Reactome | ABCC1,ABCG2 transport C18-S1P to extracellular region

Schema > Reaction > Entries

ABCC1,ABCG2 transport C18-S1P to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10991150] sphingolipid transporter activity of ABCC1,ABCG2 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10991152
displayName	ABCC1,ABCG2 transport C18-S1P to extracellular region
eventOf	[Pathway:R-CEL-1660661] Sphingolipid de novo biosynthesis - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-428690] PLPP1 dephosphorylates extracellular sphingosine-1-phosphate - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-9843721] ABCC1,ABCG2 transport C18-S1P to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-428203] C18-S1P [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCC1,ABCG2 transport C18-S1P to extracellular region
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-419305] C18-S1P [extracellular region] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-CEL-428273] SPHK1 phosphorylates sphingoid - Caenorhabditis elegans [Reaction:R-CEL-9695949] SPHK2 phosphorylates sphingoid - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9843721
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1660661] Sphingolipid de novo biosynthesis
(precedingEvent)	[Reaction:R-CEL-428690] PLPP1 dephosphorylates extracellular sphingosine-1-phosphate
(inferredTo)	[Reaction:R-HSA-9843721] ABCC1,ABCG2 transport C18-S1P to extracellular region

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