Reactome | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

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Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10994911
displayName	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
eventOf	[Pathway:R-CEL-927802] Nonsense-Mediated Decay (NMD) - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-927789] Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-975956] Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-975956
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-927802] Nonsense-Mediated Decay (NMD)
(inferredTo)	[Pathway:R-HSA-975956] Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

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