Reactome | S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated

Schema > Reaction > Entries

S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated Show undefined attributes

catalystActivity	[CatalystActivity:10812798] protein-cysteine S-palmitoyltransferase activity of ZDHHC9:GOLGA7 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10812800
displayName	S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated
eventOf	[Pathway:R-CEL-9648002] RAS processing - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-CEL-9647980] mature RAS proteins translocate to plasma membrane - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-9647982] S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated - Homo sapiens
input	[SimpleEntity:R-ALL-200993] PALM-CoA [cytosol] [EntityWithAccessionedSequence:R-CEL-9647796] S-Farn-Me HRAS [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
name	S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [DefinedSet:R-CEL-9647967] S-Farn-Me PalmS KRAS4A,HRAS, NRAS [Golgi membrane]
precedingEvent	[Reaction:R-CEL-9647977] ICMT methylates S-Farn RAS proteins - Caenorhabditis elegans
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9647982
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-9648002] RAS processing
(precedingEvent)	[BlackBoxEvent:R-CEL-9647980] mature RAS proteins translocate to plasma membrane
(inferredTo)	[Reaction:R-HSA-9647982] S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated